Endoplasmic reticulum stress in periimplantation embryos

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Endoplasmic reticulum stress in periimplantation embryos

Stress coping mechanisms are critical to minimize or overcome damage caused by ever changing environmental conditions. They are designed to promote cell survival. The unfolded protein response (UPR) pathway is mobilized in response to the accumulation of unfolded proteins, ultimately in order to regain endoplasmic reticulum (ER) homeostasis. Various elements of coping responses to ER stress inc...

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Cellular homeostasis is supported by a symphonic balancing act involving protein synthesis, folding, modification, trafficking and degradation. In eukaryotic cells the endoplasmic reticulum (ER) is a specialized organelle that is the central site of synthesis and folding of secretory, membrane and a number of organelletargeted proteins. Correct folding and post-translational modifications of th...

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ژورنال

عنوان ژورنال: Clinical and Experimental Reproductive Medicine

سال: 2015

ISSN: 2233-8233,2233-8241

DOI: 10.5653/cerm.2015.42.1.1